Establishing a left-right axis in the embryo.

نویسندگان

  • A K Ryan
  • J C Izpisúa Belmonte
چکیده

Vertebrates exhibit evolutionarily conserved asymmetries in the pattern of internal organ placement that are essential for their normal physiological function. Left-right asymmetries in organ situs are dependent upon the formation of an intact left-right axis during embryogenesis. Recently many of the molecular components involved in the initiation and maintenance of the left-right axis have been described. These molecules and their function in promoting left-right asymmetries are reviewed.

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عنوان ژورنال:
  • IUBMB life

دوره 50 1  شماره 

صفحات  -

تاریخ انتشار 2000